URINE PROTEIN CREATININE RATIO

UPCR is a laboratory test performed to determine the presence and severity of protein in the urine. It is also important to diagnose kidney damage or kidney disease If ever protein is present in the urine in a measurable amount. The test evaluates the amount of protein present in relation to the amount of creatinine in a urine sample, thus yielding one single value. This method provides a better approach for diagnosing kidney problems than the dipstick method.

When working with a urine sample, healthcare practitioners analyse the specimen to estimate the concentration of creatinine and protein. Using a dip assay identifies the protein content in urine sample, along with the creatinine level. Since creatinine is a stable waste substance that moves in the body in a steady rate, it means there is little variation in the creatinine level in urine. Thus, the argument of protein deficiency or surplus can be accurately estimated.

The UPCR Test assesses the ratio of protein present and creatinine in a urine sample. It is commonly reported as a ratio in mg of protein over grams of creatinine (mg/g Cr). This ratio is useful in determining the degree of proteinuria, and to measure any kidney damage or disease.

The UPCR exam is most administered for the reasons below:

• Kidney disease screening for patients who have diabetes, high blood pressure or have a family history of kidney disease.
• To assess kidney function in patients with a known kidney disease.
• To establish kidney damage or disease in patients who have haematuria or proteinuria symptoms.

The UPCR exam is generally considered as a low risk and non-intrusive exam. However, there are some limitations to the test:

• Failing to detect proteinuria with patients who have some degree of kidney damage.
• Demonstrate misleading results because of urine sample contamination or some medications taken by the patients.
• Not applicable for those having advanced stages of kidney disease or people who are into dialysis therapy.

The UPCR tests evaluates the following parameters:

• The concentration of protein in the urine (mg/dL)
• The concentration of creatinine in urine(g/dL)
• The protein to creatinine ratio (mg/g Cr)

These parameters will determine the extent of proteinuria and the potential diagnosis of kidney damage or disease.

The people that should take a UPCR test include the following:

• People that already have an existing case of kidney disease and requires frequent monitoring of their kidney functions.
• A person that has Polycystic Kidney disease or has a risk factor such as high blood pressure, increasing family health issues, blood sugar diabetes etc.
• A person that shows signs of having proteinuria or haematuria.

Some of the benefits include: UPCR test helps in spotting, monitoring, and even diagnosing the medical condition.

• If there are any signs of the high-risk factors present, a physician can treat them before any further damage is done.
• For those who are suffering with chronic kidney disease, worrying about the condition deteriorating is not an issue, since the level of the disease is easily monitored.
• And in case er, any A chronic symptoms such as proteinuria or even blood joined by the others shows up, the condition too can easily be treated.

UPCR, as a relative finding, can diagnose:

• Any traces of Abnormal Polycystic Kidneys.
• Damage or any chronic disease of the kidneys
• Kidney diseases such as:
• Nephrotic Syndrome.
• Glomerulonephritis

To get ready for the test:

• Ensure that your personal physician is aware of all the medications that you take or change medications with.
• Either provide a urine sample within a 24-hour period, or you can collect one sample at random.

Do not mix urine samples with any blood or other fluids

Prerequisite: None

Who are Eligible: Everyone is eligible for the UPCR test.

How to Take the Test: Collect Urine Sample

Things to do Before the Test: Check with your professional concerning any drugs you have been using lately.